Endocrine Abstracts

Objectives: To analyze the presence of correlation between DHEA-S level and glycemic indices at CGMS of intercellular fluid according to the regularity of menstrual cycle of women with type 1 diabetes mellitus.Methods: The study of daily dynamics of glucose has been performed with continuous glucose monitoring system (CGMS) Medtronik MINIMED company, the USA. The study involved 155 patients with type 1 diabetes mellitus. The patients were divided into 2 ...

Study objective: To determine risk factors of hypoglycemic episodes among patients with type 1 diabetes mellitus (T1D) using the continuous glucose monitoring system (CGMS).Materials and methods: Total 120 female patients with T1D were examined. The 1st group was with concealed hypoglycemic episodes (n=79) that has made 66% and the 2nd group was with frank hypoglycemic episodes (n=41) that has made 31% of the total number of the examined. T...

ObjectiveTo identify risk factors affecting the severity of glycemic variability indicators in patients with diabetes mellitus type 2.Materials and methodsThe study included 92 patients with diabetes mellitus type 2 and an average age of 62.25 ± 9.52 years. A biochemical blood test was performed on an automated Cobas 6000 system. To assess the glycemic variability, the standard deviation (SD</smal...

ObjectiveTo evaluate the frequency of common risk factors for depression development in patients with the diabetes mellitus of the type 2 (DM 2).Materials and methods163 patients with DM 2 at the age of 40–65 years old, period of DM is 11.18 [4.28; 22.33] years. The evaluation of the anxiety and depression level was carried out with the use of the Hospital anxiety and depression scale (HADS); a ...

The objective is to assess the presence of possible correlation between the calculated body fat percentage (BFP) indicator and indicators of metabolic control in women of reproductive age with polycystic ovarian syndrome (PCOS).Materials and Methods: The study included 80 women with a diagnosed PCOS according to the Rotterdam criteria. All study participants underwent standard general clinical studies with the determination of body mass index (BMI), wais...

Purpose: To evaluate the possible risk factors for depression development in type 1 diabetes mellitus (DM 1).Methods: 163 patients with DM 1. Depression was determined by the hospital anxiety and depression scale (HADS). Common factors of risk depression development were assessed by questionnaire survey according to a specially designed questionnaire. The levels of HbA1c and homocysteine (HC) serum were determined.Results: Depressi...

Objectives: To analyze the indicators of carbohydrate metabolism depending on the characteristics of the manifestation of hypoglycemic reactions.Materials and methods: The study daily glucose dynamics was carried out with Medtronik MINIMED Continious Glucose Monitoring System (CGMS), USA.The standard glycose profile (4–5 per day) was measured in capillary blood with the Precision PCχTM glucose meter, MediSense. To analyz...

To study anxiety frequency in school-aged children with diabetes mellitus type 1 (DM type 1) depending on carbohydrate metabolism compensation.Materials and methods: 96 patients with DM type 1 aged 13.9 ± 1.97 years. Diabetes duration is 1.72 ± 22.33 Year. We determined glycated hemoglobin (НbA1). The level of HbA1 of 7.5% or more indicated the decompensation of carbohydrate metabolism. Evaluation of the anxiety level was carried out usin...

Objective to assess homocysteine and B12 basal levels in patients with diabetes mellitus type 1 (DM type 1) depending on anxiety level.Materials and methods: 163 patients with DM type 1 aged 18–65 years. Diabetes duration is 11.18 [4.28; 22.33] years. The level of anxiety was assessed according to the HADS scale. The homocysteine and vitamin B12 level in serum was determined. Depending on the anxiety level according to the results of the HADS score...

The aim of the study was to assess the effectiveness of postmenopausal osteoporosis (PMOP) therapy with denosumab.Patients and methods 32 postmenopausal women with established PMOP for a period of 24 months or more received denosumab 60 mg subcutaneously once every 6 months combined with calcium and vitamin D. A quantitative assessment of bone mineral density (BMD) was carried out before treatment, after 12 and 24 months of observation, using dual-energy X-ray absorptiometry o...